Researchers announce the first patient has been dosed in a trial testing remestemcel-L, a stem cell therapy, in severe COVID-19 patients on ventilators. Testing of an experimental COVID-19 stem cell therapy has begun in the US. The therapy has been developed to treat hospitalized COVID-19 patients with moderate to severe acute respiratory distress syndrome (ARDS) who are on ventilators. A total of 300 are expected to be recruited into the randomized, placebo-controlled trial. The trial, in which patients will either receive the drug remestemcel-L or a placebo in addition to the recommended standard of care, is being conducted by the University of Maryland School of Medicine (UMSOM) researchers at the University of Maryland Medical Center (UMMC) and additional sites across the US. The first patient was treated at UMMC.
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100 million adults in the United States - The majority of chronic pain in the United States is the result of a musculoskeletal injury stemming from trauma, disease, or illness. It is estimated that more than 100 million adults in the United States deal with some form of back pain throughout the year. And for many of these individuals, their back pain gradually goes from being acute to chronic.
Chronic pain is like a thief that can deprive your life of its joy. It can leave you with a terrible sense of hopelessness. Chronic pain sufferers find themselves receding into a routine that is dominated by a constant struggle to focus on life in spite of the pain. Everything else falls to the wayside. The things that they love to do, the things that give their life joy and meaning, become impossible. Depression quickly sets in, and a person who is battling chronic pain can lose hope that their life will ever return to what it was before. If you are currently battling chronic pain, we empathize with what you are going through.
Researchers urge measured optimism about new studies on stem cell treatments for heart issues, rotator cuff injuries, and hair loss. Stem cells have been touted as treatments for everything from hair loss to heart disease. But are those claims scientifically sound? Research on the technology continues to look promising, but many of its human applications are still preliminary and their effectiveness anecdotal. Samumed, a $12 billion biotech start-up based in San Diego, profiled in Business Insider, exemplifies both sides of the coin.
Using sheep, whose knees are similar to human knees, researchers got the meniscus to regrow itself by implanting a biodegradable plastic device to lure stem cells and help them grow. Every year about 1 million people have surgery to repair a tear in the meniscus of their knee, according to the American Academy of Orthopedic Surgeons. It’s an injury that can’t be fully fixed since cartilage doesn’t repair itself very well. Even patients who have surgery often go on to develop arthritis. Some eventually need a knee replacement.
Rheumatoid arthritis is an autoimmune condition that mainly affects the joints. Stem cell therapy is a relatively new area of research that is showing promise in treating autoimmune conditions such as this. In rheumatoid arthritis (RA), the immune system mistakenly attacks the tissue that lines the joints, which can cause pain, inflammation, swelling, and stiffness.
Overview - Throughout the United States, stem cell therapy is being touted as a miracle cure for everything from wrinkles to spinal repair. Though very few of these applications have any scientific backing, stem cell therapy for knees has been the subject of quite a few promising studies. Arthritis develops when the cartilage lining the joints starts to deteriorate, causing pain and limiting function. Osteoarthritis is incredibly common. Arthritis and similar conditions are a major cause of disability in the United States.
Studies show that most of us experience back pain at some point in our lives. Back pain has a wide range of causes; it can originate from a severe spine injury, sports injury, accidents, or even bad posture. More often than not, the constant wear and tear of the spine induce back pain. Apart from that, an injury that has aggravated over the years can also lead to excruciating pain in the back.
It is accepted that the cartilage in our joints does not have the ability to heal itself due to lack of blood supply. Currently, there are not many effective treatments for cartilage regeneration. Stem cells may be an answer. A recent Phase III clinical trial at the Medical Center for Translational Research (MTR) of Osaka University looks into the effectiveness of stem cells in regenerating cartilage tissues.
To understand why stem cell platelet-rich plasma or co-transplantation of Adipose-derived mesenchymal stem cells and PRP is such a remarkable idea in regenerative medicine, let’s spend a little time looking at the mechanics of PRP.
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